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LACTB2 Antibody

  • 货号：
    CSB-PA012717GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q53H82
  • 基因名：
    LACTB2
  • 别名：
    Beta lactamase like protein 2 antibody; Beta-lactamase-like protein 2 antibody; CGI 83 antibody; CGI-83 antibody; LACB2_HUMAN antibody; Lactamase beta 2 antibody; LACTB2 antibody; MGC112672 antibody; MGC140671 antibody; MGC7674 antibody; OTTHUMP00000226691 antibody; OTTHUMP00000226692 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human LACTB2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
  • 基因功能参考文献：
    1. This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism PMID: 27005419
    2. this study discovered that LACTB2 is an endoribonuclease that is involved in the turnover of mitochondrial RNA, and is essential for mitochondrial function in human cells. PMID: 26826708
    3. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer PMID: 25823027
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Metallo-beta-lactamase superfamily, Glyoxalase II family
  • 数据库链接：

    HGNC: 18512

    KEGG: hsa:51110

    STRING: 9606.ENSP00000276590

    UniGene: Hs.118554