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LAIR2 Antibody

  • 货号：
    CSB-PA313669
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA313669(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA313669(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q6ISS4
  • 基因名：
    LAIR2
  • 别名：
    CD306 antibody; CD306 antigen antibody; LAIR 2 antibody; LAIR-2 antibody; LAIR2 antibody; LAIR2_HUMAN antibody; Leukocyte associated Ig like receptor 2 antibody; Leukocyte associated immunoglobulin like receptor 2 antibody; Leukocyte-associated immunoglobulin-like receptor 2 antibody; MGC71634 antibody; OTTHUMP00000068389 antibody; OTTHUMP00000068390 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human LAIR2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. recombinant LAIR-2-Fc inhibits complement-mediated lysis of cells sensitized with anti-HLA antibodies PMID: 24192271
    2. the presence of high LAIR-2 levels in 74/80 sera from patients with autoimmune thyroid diseases PMID: 23691008
    3. LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion PMID: 23332415
    4. Two markers in two different genes (CNOT3 and LAIR2) showed significant association with ankylosing spondylitis. PMID: 22294640
    5. LAIR-2/Fc has the capacity to interfere with platelet-collagen interactions mediated by Glycoprotein VI and the VWF/Glycoprotein Ib axis. PMID: 20730098
    6. Human collagen II peptides II-17, -27, -30, -35, -38, -42, -49 & -56; and collagen III peptides III-1, 5, -8, -10, -12, -13, -22, -30, -38, -40, -44, -45, and -51 specifically interacted with hLAIR-2 expressed on K562 cells PMID: 19345263

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  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    HGNC: 6478

    OMIM: 602993

    KEGG: hsa:3904

    STRING: 9606.ENSP00000301202

    UniGene: Hs.43803