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LEMD2 Antibody

  • 货号：
    CSB-PA854097LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate
      All lanes: LEMD2 antibody at 6.95µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 57, 24 kDa
      Observed band size: 57 kDa
    • IHC image of CSB-PA854097LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LEMD2 Polyclonal antibody
  • Uniprot No.：
    Q8NC56
  • 基因名：
    LEMD2
  • 别名：
    LEMD2; LEM domain-containing protein 2; hLEM2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human LEM domain-containing protein 2 protein (17-204AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LEMD2 Antibody (CSB-PA854097LA01HU)，的标记方式是Non-conjugated。对于LEMD2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA854097LB01HU LEMD2 Antibody, HRP conjugated ELISA
    FITC CSB-PA854097LC01HU LEMD2 Antibody, FITC conjugated
    Biotin CSB-PA854097LD01HU LEMD2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope.; Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling.
  • 基因功能参考文献：
    1. We conclude that Lem2p/LEM2 is a conserved nuclear site-specific adaptor that recruits Cmp7p/CHMP7 and downstream ESCRT factors to the nuclear envelope. PMID: 28242692
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445
  • 相关疾病：
    Cataract 46, juvenile-onset (CTRCT46)
  • 亚细胞定位：
    Nucleus inner membrane; Multi-pass membrane protein. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    HGNC: 21244

    OMIM: 212500

    KEGG: hsa:221496

    STRING: 9606.ENSP00000293760

    UniGene: Hs.444845