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  4. LEPREL2 Antibody

LEPREL2 Antibody

  • 货号：
    CSB-PA075987
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human rectal cancer tissue using CSB-PA075987(LEPREL2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human placenta tissue using CSB-PA075987(LEPREL2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A549 cells, mouse heart tissue, Hela cells, Primary antibody: CSB-PA075987(LEPREL2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q8IVL6
  • 基因名：
    P3H3
  • 别名：
    P3H3 antibody; LEPREL2 antibody; Prolyl 3-hydroxylase 3 antibody; EC 1.14.11.7 antibody; Leprecan-like protein 2 antibody; Protein B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human LEPREL2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.
  • 亚细胞定位：
    Endoplasmic reticulum.
  • 蛋白家族：
    Leprecan family
  • 组织特异性：
    Detected in fetal cartilage (at protein level). Weak expression in heart, lung, ovary and skeletal muscle.
  • 数据库链接：

    HGNC: 19318

    OMIM: 610342

    KEGG: hsa:10536

    STRING: 9606.ENSP00000379951

    UniGene: Hs.631655