LRIG2 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) LRIG2 Polyclonal antibody
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Uniprot No.:O94898
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基因名:LRIG2
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别名:KIAA0806 antibody; Leucine rich repeats and immunoglobulin like domains 2 antibody; Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody; LIG-2 antibody; LIG2 antibody; LRIG2 antibody; LRIG2_HUMAN antibody; UFS2 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 protein (833-932AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,LRIG2 Antibody (CSB-PA013085LA01HU),的标记方式是Non-conjugated。对于LRIG2 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB, IF
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:5000 IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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基因功能参考文献:
- Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
- Role of LRIG2 in cancer [review] PMID: 27628597
- LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
- A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
- Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
- LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
- LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
- LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
- This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012
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相关疾病:Urofacial syndrome 2 (UFS2)
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亚细胞定位:Cell membrane; Single-pass type I membrane protein. Cytoplasm.
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组织特异性:Detected in all tissues analyzed.
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数据库链接:
HGNC: 20889
OMIM: 608869
KEGG: hsa:9860
STRING: 9606.ENSP00000355396
UniGene: Hs.448972