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LSM1 Antibody

  • 货号：
    CSB-PA013199LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013199LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA013199LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LSM1 Polyclonal antibody
  • Uniprot No.：
    O15116
  • 基因名：
    LSM1
  • 别名：
    Cancer associated Sm like protein antibody; Cancer associated Sm-like antibody; Cancer-associated Sm-like antibody; CASM antibody; lsm1 antibody; LSM1 antibody antibody; LSM1 homolog; U6 small nuclear RNA associated (S. cerevisiae) antibody; Lsm1 protein antibody; LSM1; U6 small nuclear RNA associated antibody; LSM1_HUMAN antibody; Small nuclear ribonuclear CaSm antibody; U6 snRNA associated Sm-like protein LSm1 antibody; U6 snRNA-associated Sm-like protein LSm1 antibody; YJL124C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human U6 snRNA-associated Sm-like protein LSm1 protein (1-133AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LSM1 Antibody (CSB-PA013199LA01HU)，的标记方式是Non-conjugated。对于LSM1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA013199LB01HU LSM1 Antibody, HRP conjugated ELISA
    FITC CSB-PA013199LC01HU LSM1 Antibody, FITC conjugated
    Biotin CSB-PA013199LD01HU LSM1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
  • 基因功能参考文献：
    1. These results provide evidence that LSm1 binding to the DENV RNA 3' UTR positively regulates DENV RNA replication. PMID: 25872476
    2. The results of this study provided further support for previous genetic findings reporting the association of an intronic SNP (rs16887244) in LSM1 and schizophrenia in a Chinese sample PMID: 24035562
    3. Lsm1 is deeply involved in prostate cancer progression through its down-regulation, independent of any gene mutation. PMID: 11953827
    4. LSM1 is a breast cancer oncogene from the 8p11-12 amplicon. PMID: 17001308
    5. Results suggest that LSm-1/CaSm functions as an oncogene in the promotion of cellular transformation and cancer progression. PMID: 18218995

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, P-body.
  • 蛋白家族：
    SnRNP Sm proteins family
  • 数据库链接：

    HGNC: 20472

    OMIM: 607281

    KEGG: hsa:27257

    STRING: 9606.ENSP00000310596

    UniGene: Hs.425311