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LSR Antibody

  • 货号：
    CSB-PA013215GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q86X29
  • 基因名：
    LSR
  • 别名：
    ILDR3 antibody; Immunoglobulin like domain containing receptor 3 antibody; Lipolysis Stimulated Lipoprotein Receptor antibody; Lipolysis stimulated remnant antibody; Lipolysis-stimulated lipoprotein receptor antibody; LISCH antibody; LISCH protein antibody; LISCH7 antibody; Liver specific bHLH Zip transcription factor antibody; LSR antibody; LSR_HUMAN antibody; MGC10659 antibody; MGC48312 antibody; MGC48503 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human LSR
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
  • 基因功能参考文献：
    1. this study shows that loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in endometrial cancer PMID: 28071680
    2. Lipolysis-stimulated lipoprotein receptor (LSR)-deficient CaCo-2 cells exhibited increased cell proliferation. PMID: 27391068
    3. Results of this study provide novel evidence that tricellular tight junctions protein LSR negatively regulates cancer cell progression and development in endometrial cancer. PMID: 27036040
    4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1) localized to the bicellular regions. PMID: 28493278
    5. analysis of how Clostridium difficile binary toxin CDT interacts with its host cell receptor, Lipolysis-stimulated Lipoprotein Receptor PMID: 25882847
    6. These data show that Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts. PMID: 23631918
    7. findings show that Clostridium spiroforme toxin (CST)enters target cells via the lipolysis-stimulated lipoprotein receptor; findings indicate that CST shares LSR with C. difficile CDT and C. perfringens iota toxin as a host cell surface receptor PMID: 22252869
    8. LSR defines tricellular contacts in epithelial cellular sheets by acting as a landmark to recruit tricellulin for tricellular tight junction formation. PMID: 21245199
    9. LISCH7 may have a role in progression of human colon cancer PMID: 17975147

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  • 亚细胞定位：
    Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, LISCH7 family
  • 数据库链接：

    HGNC: 29572

    OMIM: 616582

    KEGG: hsa:51599

    STRING: 9606.ENSP00000354575

    UniGene: Hs.466507