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MAB21L1 Antibody

  • 货号：
    CSB-PA623800LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: MAB21L1 antibody at 6µg/ml
      Lane 1: A375 whole cell lysate
      Lane 2: CEM whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 41 kDa
      Observed band size: 41 kDa
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA623800LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MAB21L1 Polyclonal antibody
  • Uniprot No.：
    Q13394
  • 基因名：
    MAB21L1
  • 别名：
    MAB21L1 antibody; CAGR1 antibody; Nbla00126Putative nucleotidyltransferase MAB21L1 antibody; EC 2.7.7.- antibody; Protein mab-21-like 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Putative nucleotidyltransferase MAB21L1 protein (1-359AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MAB21L1 Antibody (CSB-PA623800LA01HU)，的标记方式是Non-conjugated。对于MAB21L1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA623800LB01HU MAB21L1 Antibody, HRP conjugated ELISA
    FITC CSB-PA623800LC01HU MAB21L1 Antibody, FITC conjugated
    Biotin CSB-PA623800LD01HU MAB21L1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye. It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA).
  • 基因功能参考文献：
    1. Mab21l1-/- osteoblasts also expressed higher levels of adipocyte genes and interferon-regulated genes at early stages of osteogenesis PMID: 29156428
    2. offer a structure-based explanation for the effects of MAB21L2 mutations in patients with eye malformations PMID: 27271801
    3. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
    4. We hypothesize that MAB21L1 haploinsufficiency cause a previously undescribed syndrome with scrotal agenesis, ophthalmological anomalies, facial dysmorphism and gross psychomotor delay as remarkable hallmarks. PMID: 27103078
    5. MEF is involved in PTH suppression of osteoblasts through activating the MKK4/JNK1 pathway and subsequently up-regulating Mab21l1 expression. PMID: 21465527

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Mab-21 family
  • 组织特异性：
    Expressed in brain, cerebellum and skeletal muscle.
  • 数据库链接：

    HGNC: 6757

    OMIM: 601280

    KEGG: hsa:4081

    STRING: 9606.ENSP00000369251

    UniGene: Hs.584776