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MAP7 Antibody

  • 货号：
    CSB-PA013443GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q14244
  • 基因名：
    MAP7
  • 别名：
    dJ325F22.2 (microtubule-associated protein 7 (EMAP115; E-MAP- 115)) antibody; E MAP 115 antibody; E-MAP-115 antibody; EMAP115 antibody; Ensconsin antibody; Epithelial microtubule associated protein of 115 kDa antibody; Epithelial microtubule-associated protein of 115 kDa antibody; MAP 7 antibody; MAP-7 antibody; Map7 antibody; MAP7_HUMAN antibody; Microtubule associated protein 7 antibody; Microtubule-associated protein 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MAP7
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
  • 基因功能参考文献：
    1. findings demonstrate the efficacy of quantitative proteomics for identifying effector-host protein interactions and suggest that vesicular trafficking is a crucial cellular process that may be targeted by NleB1 and EspL through their interaction with ensconsin. PMID: 27018634
    2. Study of 117 patients suggests MAP7 as a candidate gene for sacral dysgenesis. However, we were unable to detect any sacral defects in the MAP7 knockout mice. PMID: 15218243
    3. the expression ratio of Map7/B2M may serve as a valuable prognostic marker in patients with Stage II colon cancer PMID: 18695889
  • 亚细胞定位：
    Cytoplasm, perinuclear region. Basolateral cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike-like bundles facing intercellular contacts.
  • 蛋白家族：
    MAP7 family
  • 组织特异性：
    Expressed in the skin and cells of epithelial origin. Predominantly expressed in the suprabasal layers of the normal epidermis and relatively abundant in squamous cell carcinomas but barely detectable in basal cell carcinomas.
  • 数据库链接：

    HGNC: 6869

    OMIM: 604108

    KEGG: hsa:9053

    STRING: 9606.ENSP00000414712

    UniGene: Hs.486548