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MAP9 Antibody

  • 货号：
    CSB-PA060167
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q49MG5
  • 基因名：
    MAP9
  • 别名：
    ASAP antibody; Aster associated protein antibody; Aster-associated protein antibody; Map9 antibody; MAP9_HUMAN antibody; microtubule associated protein 9 antibody; Microtubule-associated protein 9 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MAP-9.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
  • 基因功能参考文献：
    1. MAP9 downregulation is associated with colorectal malignancy. PMID: 24876664
    2. ASAP stabilizes p53 both by alleviating MDM2-mediated p53 ubiquitination and by enhancing its p300-dependent acetylation. PMID: 22672907
    3. Results highlight dual ASAP regulation by Plk1 and further confirm the importance of ASAP for spindle pole organization, bipolar spindle assembly, and mitosis. PMID: 20615875
    4. ASAP is a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. PMID: 16049101
    5. Study demonstrates that AurA-mediated phosphorylation of ASAP is essential to spindle formation and mitosis. PMID: 17925329

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
  • 数据库链接：

    HGNC: 26118

    OMIM: 610070

    KEGG: hsa:79884

    STRING: 9606.ENSP00000310593

    UniGene: Hs.61271