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MARVELD3 Antibody

  • 货号：
    CSB-PA842633LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of Hela cells with CSB-PA842633LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MARVELD3 Polyclonal antibody
  • Uniprot No.：
    Q96A59
  • 基因名：
    MARVELD3
  • 别名：
    MARVELD3; MRVLDC3; MARVEL domain-containing protein 3
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human MARVEL domain-containing protein 3 protein (1-189AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MARVELD3 Antibody (CSB-PA842633LA01HU)，的标记方式是Non-conjugated。对于MARVELD3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842633LB01HU MARVELD3 Antibody, HRP conjugated ELISA
    FITC CSB-PA842633LC01HU MARVELD3 Antibody, FITC conjugated
    Biotin CSB-PA842633LD01HU MARVELD3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    As a component of tight junctions, plays a role in paracellular ion conductivity.
  • 基因功能参考文献：
    1. MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. PMID: 24567356
    2. MarvelD3 is transcriptionally downregulated in Snail-induced epithelial-mesenchymal transition during the progression for the pancreatic cancer. PMID: 21763689
    3. marvelD3, occludin, and tricellulin define the tight junction-associated MARVEL protein family PMID: 20164257
    4. MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells. PMID: 20028514
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, tight junction.
  • 数据库链接：

    HGNC: 30525

    OMIM: 614094

    KEGG: hsa:91862

    UniGene: Hs.513706