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MED24 Antibody

  • 货号：
    CSB-PA004328
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using TRAP100 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O75448
  • 基因名：
    MED24
  • 别名：
    CRSP complex subunit 4 antibody; Activator recruited cofactor 100 kDa component antibody; Activator-recruited cofactor 100 kDa component antibody; ARC100 antibody; Cofactor required for Sp1 transcriptional activation subunit 4 antibody; CRSP complex subunit 4 antibody; CRSP100 antibody; CRSP4 antibody; DRIP100 antibody; hTRAP100 antibody; KIAA0130 antibody; MED 24 antibody; MED24 antibody; MED24_HUMAN antibody; Mediator complex subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 homolog antibody; MGC8748 antibody; OTTHUMP00000164458 antibody; OTTHUMP00000164460 antibody; THRAP4 antibody; Thyroid hormone receptor associated protein 4 antibody; Thyroid hormone receptor associated protein complex 100 kDa component antibody; Thyroid hormone receptor-associated protein 4 antibody; Thyroid hormone receptor-associated protein complex 100 kDa component antibody; Trap100 antibody; Trapp100 antibody; Vitamin D3 receptor interacting protein complex component DRIP100 antibody; Vitamin D3 receptor-interacting protein complex 100 kDa component antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human TRAP100.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能参考文献：
    1. this study shows that haplotypes consisting of single nucleotide polymorphisms harboring PSMD3, CSF3 and MED24 genes are associated with asthma in Slovenian patients PMID: 27163155
    2. Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24, and PSMD3 in European continent (EA) subjects. PMID: 22037903
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 24 family
  • 组织特异性：
    Ubiquitous. Abundant in skeletal muscle, heart and placenta.
  • 数据库链接：

    HGNC: 22963

    OMIM: 607000

    KEGG: hsa:9862

    STRING: 9606.ENSP00000377686

    UniGene: Hs.462983