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MEGF8 Antibody

  • 货号：
    CSB-PA002262
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using EGFL4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q7Z7M0
  • 基因名：
    MEGF8
  • 别名：
    MEGF8 antibody; C19orf49 antibody; EGFL4 antibody; KIAA0817 antibody; Multiple epidermal growth factor-like domains protein 8 antibody; Multiple EGF-like domains protein 8 antibody; Epidermal growth factor-like protein 4 antibody; EGF-like protein 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human EGFL4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a negative regulator of hedgehog signaling.
  • 基因功能参考文献：
    1. mutations in MEGF8 cause a Carpenter syndrome subtype frequently associated with defective left-right patterning, probably through perturbation of signaling by hedgehog and nodal family members. PMID: 23063620
  • 相关疾病：
    Carpenter syndrome 2 (CRPT2)
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 数据库链接：

    HGNC: 3233

    OMIM: 604267

    KEGG: hsa:1954

    STRING: 9606.ENSP00000334219

    UniGene: Hs.132483