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MINPP1 Antibody

  • 货号：
    CSB-PA891977EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: MINPP1 antibody at 14μg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: U251 whole cell lysate
      Lane 3: K562 whole cell lysate
      Lane 4: Hela whole cell lysate
      Lane 5: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 56, 35, 32, 34 kDa
      Observed band size: 56 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA891977EA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MINPP1 Polyclonal antibody
  • Uniprot No.：
    Q9UNW1
  • 基因名：
    MINPP1
  • 别名：
    3 antibody; 4 antibody; 5)-tetrakisphosphate 3-phosphatase antibody; 5)P(4) 3-phosphatase antibody; DKFZp564L2016 antibody; HIPER1 antibody; Inositol (1 antibody; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody; Ins(1 antibody; ins(1,3,4,5)P(4) 3-phosphatase antibody; MINP1_HUMAN antibody; Minpp1 antibody; MINPP2 antibody; MIPP antibody; Multiple inositol polyphosphate histidine phosphatase, 1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; multiple inositol polyphosphate phosphatase 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Multiple inositol polyphosphate phosphatase 1 protein (31-487AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MINPP1 Antibody (CSB-PA891977EA01HU)，的标记方式是Non-conjugated。对于MINPP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA891977EB01HU MINPP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA891977EC01HU MINPP1 Antibody, FITC conjugated
    Biotin CSB-PA891977ED01HU MINPP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
  • 基因功能参考文献：
    1. Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
    2. By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306
  • 相关疾病：
    Thyroid cancer, non-medullary, 2 (NMTC2)
  • 亚细胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Histidine acid phosphatase family, MINPP1 subfamily
  • 组织特异性：
    Widely expressed with highest levels in kidney, liver and placenta.
  • 数据库链接：

    HGNC: 7102

    OMIM: 188470

    KEGG: hsa:9562

    STRING: 9606.ENSP00000361064

    UniGene: Hs.121260