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  4. MOBP Antibody

MOBP Antibody

  • 中文名称：
    MOBP兔多克隆抗体
  • 货号：
    CSB-PA014701GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13875
  • 基因名：
    MOBP
  • 别名：
    MOBP antibody; Myelin-associated oligodendrocyte basic protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MOBP
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
  • 基因功能参考文献：
    1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
    2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
    3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
    4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
    5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117

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  • 亚细胞定位：
    Cytoplasm, perinuclear region.
  • 数据库链接：

    HGNC: 7189

    OMIM: 600948

    KEGG: hsa:4336

    UniGene: Hs.121333