Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. MOCOS Antibody

MOCOS Antibody

  • 货号：
    CSB-PA014702GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96EN8
  • 基因名：
    MOCOS
  • 别名：
    MOCOS antibody; Molybdenum cofactor sulfurase antibody; MCS antibody; MOS antibody; MoCo sulfurase antibody; hMCS antibody; EC 2.8.1.9 antibody; Molybdenum cofactor sulfurtransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MOCOS
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.
  • 基因功能参考文献：
    1. MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH) and aldehyde oxidase 1 (AOX1), which is required for their activities. PMID: 22495427
    2. Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria. PMID: 17368066
  • 相关疾病：
    Xanthinuria 2 (XAN2)
  • 蛋白家族：
    Class-V pyridoxal-phosphate-dependent aminotransferase family, MOCOS subfamily
  • 数据库链接：

    HGNC: 18234

    OMIM: 603592

    KEGG: hsa:55034

    STRING: 9606.ENSP00000261326

    UniGene: Hs.405028