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MRPS22 Antibody

  • 货号：
    CSB-PA003308
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COS7 cells using MRP-S22 Polyclonal Antibody
    • Western blot analysis of mouse-brain 293T lysis using MRP-S22 antibody.
  • 其他：

产品详情

  • Uniprot No.：
    P82650
  • 基因名：
    MRPS22
  • 别名：
    28S ribosomal protein S22 antibody; C3orf5 antibody; COXPD5 antibody; GIBT antibody; GK002 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S22 antibody; MRP-S22 antibody; MRPS22 antibody; RPM S22 antibody; RPMS22 antibody; RT22_HUMAN antibody; S22mt antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Monkey
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MRP-S22.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. hypertrophic cardiomyopathy and tubulopathy may not be considered as constant features of MRPS22 PMID: 28752220
    2. A mutation in the MRPS22 gene led to reduction of 12sRNA in fibroblasts and fatal neonatal hypertrophic cardiomyopathy & kidney tubulopathy. PMID: 17873122
    3. The effect of mutated MRPS22 on the assembly of the small and large ribosomal subunits in human mitochondria is reported. PMID: 18539099
  • 相关疾病：
    Combined oxidative phosphorylation deficiency 5 (COXPD5)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS22 family
  • 数据库链接：

    HGNC: 14508

    OMIM: 605810

    KEGG: hsa:56945

    STRING: 9606.ENSP00000310785

    UniGene: Hs.745001