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MRPS27 Antibody

  • 货号：
    CSB-PA003310
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using MRP-S27 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q92552
  • 基因名：
  • 别名：
    28S ribosomal protein S27 antibody; 28S ribosomal protein S27, mitochondrial antibody; KIAA0264 antibody; Mitochondrial 28S ribosomal protein S27 antibody; mitochondrial antibody; mitochondrial ribosomal protein S27 antibody; MRP-S27 antibody; MRPS27 antibody; RT27_HUMAN antibody; S27mt antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human MRP-S27.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth.
  • 基因功能参考文献：
    1. we verified for the first time that mitochondrial ribosomal protein S23 expression was upregulated in hepatocellular carcinoma. High mitochondrial ribosomal protein S23 levels can predict poor clinical outcomes in hepatocellular carcinoma, and this protein plays a key role in tumor proliferation. Therefore, mitochondrial ribosomal protein S23 may be a potential therapeutic target for hepatocellular carcinoma. PMID: 28714366
    2. MRPS27 is required for mitochondrial protein synthesis PMID: 22841715
  • 亚细胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS27 family
  • 组织特异性：
    Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous.
  • 数据库链接：

    HGNC: 14512

    OMIM: 611989

    KEGG: hsa:23107

    STRING: 9606.ENSP00000261413

    UniGene: Hs.482491