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  4. MRPS30 Antibody

MRPS30 Antibody

  • 货号：
    CSB-PA006740
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of LOVO cells using MRP-S30 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NP92
  • 基因名：
    MRPS30
  • 别名：
    28S ribosomal protein S30 antibody; 28S ribosomal protein S30; mitochondrial antibody; Mitochondrial 28S ribosomal protein S30 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S30 antibody; MRP S30 antibody; MRP-S30 antibody; MRPS30 antibody; PAP antibody; PDCD9 antibody; Programmed cell death 9 antibody; Programmed cell death protein 9 antibody; RT30_HUMAN antibody; S30mt antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human MRP-S30.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. data suggest that the strongest signal of association at 5p12 is mediated through coordinated activation of FGF10 and MRPS30, two candidate genes for breast cancer pathogenesis PMID: 27640304
    2. Among the 10 SNPs studied, rs10941679 in MRPS30 showed significant association with breast cancer risk when differences between the case and control groups in this Han Chinese population were compared. PMID: 24528085
    3. data suggest the 5p12 risk allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
    4. The risk-associated allele of rs7716600 in the 5p12 ER-positive susceptibility locus was associated with elevated expression of the nearby gene MRPS30 and decreased MRPS30 promoter methylation exclusively in ER-positive tumors. eQTL and in vitro experiments suggest this allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mL65 family
  • 组织特异性：
    Heart, skeletal muscle, kidney and liver. Lower expression in placenta and peripheral blood leukocytes.
  • 数据库链接：

    HGNC: 8769

    OMIM: 611991

    KEGG: hsa:10884

    STRING: 9606.ENSP00000424328

    UniGene: Hs.124165