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MSTO1 Antibody

  • 货号：
    CSB-PA880106LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA880106LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA880106LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MSTO1 Polyclonal antibody
  • Uniprot No.：
    Q9BUK6
  • 基因名：
    MSTO1
  • 别名：
    MSTO1 antibody; LST005 antibody; SLTP005 antibody; Protein misato homolog 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein misato homolog 1 protein (1-280AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MSTO1 Antibody (CSB-PA880106LA01HU)，的标记方式是Non-conjugated。对于MSTO1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA880106LB01HU MSTO1 Antibody, HRP conjugated ELISA
    FITC CSB-PA880106LC01HU MSTO1 Antibody, FITC conjugated
    Biotin CSB-PA880106LD01HU MSTO1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.
  • 基因功能参考文献：
    1. we have described two unrelated patients with biallelic MSTO1 mutations. Our report provides valuable information on the consequences of MSTO1 mutations for human phenotypes. PMID: 29339779
    2. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia PMID: 28544275
    3. Thus, an MSTO1 loss-of-function mutation is associated with a human disorder showing mitochondrial involvement. MSTO1 likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion. PMID: 28554942
    4. These results indicated that human Misato has a role(s) in mitochondrial distribution and morphology and that its unregulated expression leads to cell death. PMID: 17349998
  • 相关疾病：
    Myopathy, mitochondrial, and ataxia (MMYAT)
  • 亚细胞定位：
    Mitochondrion outer membrane. Cytoplasm.
  • 蛋白家族：
    Misato family
  • 组织特异性：
    Present in all cell lines tested (at protein level). Widely expressed.
  • 数据库链接：

    HGNC: 29678

    OMIM: 617619

    KEGG: hsa:55154

    UniGene: Hs.656547