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NAA20 Antibody

  • 货号：
    CSB-PA015472ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NAA20 antibody at 10μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: Rat brain tissue
      Lane 3: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 21, 13 kDa
      Observed band size: 21 kDa
    • Immunoprecipitating NAA20 in Hela whole cell lysate
      Lane 1: Rabbit control IgG instead of (1µg) instead of CSB-PA015472ESR2HU in Hela whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
      Lane 2: CSB-PA015472ESR2HU (4µg) + Hela whole cell lysate (500µg)
      Lane 3: Hela whole cell lysate (20µg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NAA20 Polyclonal antibody
  • Uniprot No.：
    P61599
  • 基因名：
    NAA20
  • 别名：
    NAA20 antibody; NAT5 antibody; N-alpha-acetyltransferase 20 antibody; EC 2.3.1.254 antibody; Methionine N-acetyltransferase antibody; N-acetyltransferase 5 antibody; N-terminal acetyltransferase B complex catalytic subunit NAA20 antibody; N-terminal acetyltransferase B complex catalytic subunit NAT5 antibody; NatB complex subunit NAT5 antibody; NatB catalytic subunit antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human N-alpha-acetyltransferase 20 protein (49-178AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
  • 基因功能参考文献：
    1. The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration. PMID: 22814378
    2. Human N-acetyltransferase complexe NatB consists of human N-acetyltransferase 3 and human MDM20. hNAT3 knockdown results in an increase in G(0)/G(1)-phase cells. PMID: 18570629
    3. hNat3 (NAT5) is the catalytic subunit and hMdm20 the auxiliary subunit of the human NatB N-terminal acetyltransferase complex. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides. PMID: 18570629
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Acetyltransferase family, ARD1 subfamily
  • 数据库链接：

    HGNC: 15908

    OMIM: 610833

    KEGG: hsa:51126

    STRING: 9606.ENSP00000335636

    UniGene: Hs.368783