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NARL Antibody

  • 货号：
    CSB-PA360208XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: NARL antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35.5 kDa
      Observed band size: 34 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P0AF28
  • 基因名：
    NARL
  • 别名：
    Nitrate/nitrite response regulator protein NarL narL frdR b1221 JW1212
  • 反应种属：
    Bacillus thuringiensis subsp. kurstaki
  • 免疫原：
    Recombinant Escherichia coli (strain K12) NARL protein
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted by either the NarX or NarQ proteins.
  • 基因功能参考文献：
    1. The NarL receiver domain operates as an on-off switch to occlude or release the output domain in a nitrate-responsive manner. PMID: 26307095
    2. NarL and NarP carboxyl-terminal domains activate transcription from Nar class II control regions. PMID: 20634237
    3. Data describe two cocrystal structures of NarL complexed with additional 20mer oligonucleotides representative of other high-affinity tail-to-tail NarL binding sites found in upstream promoter regions. PMID: 16262254
    4. binding of NarL/NarP appears to insulate the nrf promoter from the effects of integration host factor PMID: 16936015
    5. DNA-bound dimers of phospho-NarL can participate in higher-order cooperative interac PMID: 17965164
    6. Analysis of the DNA sequence of the ydhY promoter region (PydhY) revealed the presence of four heptameric sequences similar to NarL/P binding sites PMID: 18227264
    7. DNase I footprinting studies identified Fis-binding sites that overlap the yeaR promoter NarL site at position -43.5, and the ogt promoter NarL site at position -78.5, and suggest that Fis represses both promoters by displacing NarL. PMID: 19245365
    8. The s show that the global transcription factor FNR is a class II activator at the ynfEFGHI promoter and that NarL represses activation by binding to a single target that overlaps the promoter -10 element. PMID: 19251855

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  • 数据库链接：

    KEGG: ecj:JW1212

    STRING: 316385.ECDH10B_1280