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  4. NAV2 Antibody

NAV2 Antibody

  • 货号：
    CSB-PA070187
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q8IVL1
  • 基因名：
    NAV2
  • 别名：
    NAV2 antibody; HELAD1 antibody; KIAA1419 antibody; POMFIL2 antibody; RAINB1 antibody; STEERIN2Neuron navigator 2 antibody; EC 3.6.4.12 antibody; Helicase APC down-regulated 1 antibody; Pore membrane and/or filament-interacting-like protein 2 antibody; Retinoic acid inducible in neuroblastoma 1 antibody; Steerin-2 antibody; Unc-53 homolog 2 antibody; unc53H2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Neuron Navigator 2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
  • 基因功能参考文献：
    1. NAV2 and CCND2 are novel candidate prognostic markers in uterine leiomyosarcoma and uterine low-grade endometrial stromal sarcoma, respectively. PMID: 28643014
    2. The present study is the first study providing evidence of several genetic variants within the NAV2 gene influencing the risk and age at onset of Alzheimer's disease. PMID: 28778446
    3. interaction between NAV2 and 14-3-3epsilon PMID: 24161943
    4. regulated by all-trans retinoic acid in neuroblastoma cells PMID: 11904404
    5. a novel gene, termed HELAD1 (helicase, APC down-regulated 1) plays important role in colorectal carcinogenesis (HELAD1) PMID: 12214280

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Nav/unc-53 family
  • 组织特异性：
    Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
  • 数据库链接：

    HGNC: 15997

    OMIM: 607026

    KEGG: hsa:89797

    STRING: 9606.ENSP00000379394

    UniGene: Hs.502116