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NCALD Antibody

  • 货号：
    CSB-PA015510DSR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015510DSR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015510DSR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NCALD Polyclonal antibody
  • Uniprot No.：
    P61601
  • 基因名：
    NCALD
  • 别名：
    NCALD antibody; Neurocalcin-delta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Neurocalcin-delta protein (1-193AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
  • 基因功能参考文献：
    1. Neurocalcin delta is a protective spinal muscular atrophy modifier in five asymptomatic SMN1-deleted individuals carrying only four SMN2 copies. PMID: 28132687
    2. It is presumed that NCALD is related to diabetic nephropathy by promoting epithelial mesenchymal transform. PMID: 23156397
    3. Studies show that a fold recognition based model of the catalytic domain of ROS-GC1 was built, and neurocalcin delta docking simulations were carried out to define the three-dimensional features of the interacting domains of the two molecules. PMID: 18500817
    4. association of the landmark SNP with the progression of diabetic nephropathy in a 8-year prospective study PMID: 17671797
    5. The characterizes the biochemical properties of recombinant bovine neurocalcin delta, whose protein sequence is identical to the human ortholog PMID: 7852401

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  • 蛋白家族：
    Recoverin family
  • 组织特异性：
    Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.
  • 数据库链接：

    HGNC: 7655

    OMIM: 606722

    KEGG: hsa:83988

    STRING: 9606.ENSP00000220931

    UniGene: Hs.492427