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NCAM2 Antibody

  • 货号：
    CSB-PA015512LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: MCF-7 whole cell lysate
      All lanes: NCAM2 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 94, 48 kDa
      Observed band size: 94 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA015512LA01HU at dilution of 1:100
    • Immunofluorescence staining of HepG2 cells with CSB-PA015512LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NCAM2 Polyclonal antibody
  • Uniprot No.：
    O15394
  • 基因名：
    NCAM2
  • 别名：
    Cell adhesion molecule, neural, 2 antibody; MGC51008 antibody; N CAM 2 antibody; N CAM 21 antibody; N CAM2 antibody; N CAM21 antibody; N-CAM-2 antibody; NCAM 2 antibody; NCAM 21 antibody; NCAM-2 antibody; Ncam2 antibody; NCAM2_HUMAN antibody; NCAM21 antibody; Neural cell adhesion molecule 2 antibody; OCAM GPI antibody; R4B12 antibody; RB 8 neural cell adhesion molecule antibody; RB8 neural cell adhesion molecule antibody; RNCAM antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Neural cell adhesion molecule 2 protein (209-333AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NCAM2 Antibody (CSB-PA015512LA01HU)，的标记方式是Non-conjugated。对于NCAM2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA015512LB01HU NCAM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA015512LC01HU NCAM2 Antibody, FITC conjugated
    Biotin CSB-PA015512LD01HU NCAM2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
  • 基因功能参考文献：
    1. Our reported case raises the questions whether the NCAM2-deletion is the true cause of the autism spectrum disorder or only a risk factor and whether there might be any connection in NCAM2 with skull-size PMID: 27596683
    2. Abeta-dependent disruption of NCAM2 functions in Alzheimer's disease hippocampus contributes to synapse loss. PMID: 26611261
    3. A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain. PMID: 21300289
    4. High NCAM2 is associated with increased 5-Fluorouracil sensitivity in prostate and breast cancer. PMID: 21214674
    5. In the crystal structure, two Ig domains interact by domain swapping, as the two N-terminal beta-strands are interchanged. PMID: 18706912

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed most strongly in adult and fetal brain.
  • 数据库链接：

    HGNC: 7657

    OMIM: 602040

    KEGG: hsa:4685

    STRING: 9606.ENSP00000383392

    UniGene: Hs.473450