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NDUFB10 Antibody

  • 货号：
    CSB-PA003387
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using NDUFB10 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O96000
  • 基因名：
  • 别名：
    0610011B04Rik antibody; 22kDa antibody; CI PDSW antibody; CI-PDSW antibody; Complex I PDSW antibody; Complex I PDSW subunit antibody; Complex I-PDSW antibody; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 22kDa antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 antibody; NADH ubiquinone oxidoreductase PDSW subunit antibody; NADH-ubiquinone oxidoreductase PDSW subunit antibody; NDUBA_HUMAN antibody; NDUFB 10 antibody; Ndufb10 antibody; PDSW antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NDUFB10.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
  • 基因功能参考文献：
    1. findings indicate that mutations in NDUFB10 are a novel cause of complex I deficiency associated with a late stage assembly defect and emphasize the role of intermembrane space proteins for the efficient assembly of complex I. PMID: 28040730
    2. Src kinase inhibition led to a decrease in mitochondrial respiration via a specific decrease in complex I activities which is associated with a lower phosphorylation of the complex I subunit NDUFB10. PMID: 22321370
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFB10 subunit family
  • 数据库链接：

    HGNC: 7696

    OMIM: 603843

    KEGG: hsa:4716

    STRING: 9606.ENSP00000268668

    UniGene: Hs.513266