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NDUFS8 Antibody

  • 货号：
    CSB-PA015667LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat brain tissue
      All lanes: NDUFS8 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 24 kDa
      Observed band size: 24 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NDUFS8 Polyclonal antibody
  • Uniprot No.：
    O00217
  • 基因名：
  • 别名：
    CI 23kD antibody; CI-23kD antibody; Complex I 23kD antibody; Complex I-23kD antibody; EC 1.6.5.3 antibody; EC 1.6.99.3 antibody; Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8 antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8; mitochondrial antibody; NADH ubiquinone oxidoreductase 23 kDa subunit antibody; NADH-ubiquinone oxidoreductase 23 kDa subunit antibody; NDUFS8 antibody; NDUS8_HUMAN antibody; TYKY antibody; TYKY subunit antibody; Ubiquinoneiron sulfur protein 8; mitochondrial precursor antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial protein (35-210AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NDUFS8 Antibody (CSB-PA015667LA01HU)，的标记方式是Non-conjugated。对于NDUFS8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA015667LB01HU NDUFS8 Antibody, HRP conjugated ELISA
    FITC CSB-PA015667LC01HU NDUFS8 Antibody, FITC conjugated
    Biotin CSB-PA015667LD01HU NDUFS8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
  • 基因功能参考文献：
    1. Results show that NDUFS8 protein and mRNA levels are up-regulated in lung neoplasm and correlate with poor overall survival. PMID: 27516145
    2. 2 new mutations (P85L upstream from the 2 cysteine motifs that coordinate the two [4Fe-4S] clusters which generate the complex I N2 clusters, & R138H between them)suggest that this subunit is essential for either the assembly or stability of complex I. PMID: 15159508
  • 相关疾病：
    Leigh syndrome (LS)
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I 23 kDa subunit family
  • 组织特异性：
    Expressed in all tissues with the highest level in heart and skeletal muscle and the lowest level in lung.
  • 数据库链接：

    HGNC: 7715

    OMIM: 256000

    KEGG: hsa:4728

    STRING: 9606.ENSP00000315774

    UniGene: Hs.90443