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NEUROG2 Antibody

  • 货号：
    CSB-PA248806
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA248806(NEUROG2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA248806(NEUROG2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9H2A3
  • 基因名：
    NEUROG2
  • 别名：
    Atoh 4 antibody; Atoh4 antibody; bHLHa8 antibody; Class A basic helix-loop-helix protein 8 antibody; Math 4A antibody; Math4A antibody; MGC antibody; MGC46562 antibody; NEUROG 2 antibody; NEUROG2 antibody; Neurogenin-2 antibody; Neurogenin2 antibody; NGN 2 antibody; NGN-2 antibody; NGN2 antibody; NGN2_HUMAN antibody; Protein atonal homolog 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human NEUROG2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:15-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
  • 基因功能参考文献：
    1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
    2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
    3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
    4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
    5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
    6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 13805

    OMIM: 606624

    KEGG: hsa:63973

    STRING: 9606.ENSP00000317333

    UniGene: Hs.744415