Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. NINJ2 Antibody

NINJ2 Antibody

  • 中文名称：
    NINJ2兔多克隆抗体
  • 货号：
    CSB-PA885775LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA885775LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA885775LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A431 cells using CSB-PA885775LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NINJ2 Polyclonal antibody
  • Uniprot No.：
    Q9NZG7
  • 基因名：
    NINJ2
  • 别名：
    NINJ2; Ninjurin-2; Nerve injury-induced protein 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ninjurin-2 protein (17-81AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NINJ2 Antibody (CSB-PA885775LA01HU)，的标记方式是Non-conjugated。对于NINJ2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA885775LB01HU NINJ2 Antibody, HRP conjugated ELISA
    FITC CSB-PA885775LC01HU NINJ2 Antibody, FITC conjugated
    Biotin CSB-PA885775LD01HU NINJ2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues.
  • 基因功能参考文献：
    1. our study suggests that ninjurin2 is a novel regulator of endothelia inflammation and activation through TLR4 signaling pathways, and these data provided new insights into the mechanisms between NINJ2 and atherosclerosis. PMID: 28431986
    2. the AA genotype carriers had significantly increased NINJ2 mRNA expression levels in the Chinese population, suggesting that the rs3809263 G > A polymorphism is a functional single nucleotide polymorphism and a biomarker for risk of large artery atherosclerotic stroke. PMID: 26687183
    3. Data shows that common and rare variants in the NINJ2 region were nominally associated with incident ischemic stroke patients. PMID: 24959832
    4. Risk of ischemic stroke was higher especially when the carriers of rs11833579 AA NINJ2 genotype were smokers. PMID: 24664524
    5. Data suggest that the gene NINJ2 rs11833579 A/A or G/A genotype may bring forward the onset age of first-ever ischemic stroke without increasing silent cerebrovascular lesions prior to the stroke. PMID: 22429733
    6. This meta-analysis suggest that rs12425791 is relative to ischemic stroke risk under dominant model in Asian population, but not for rs11833579. PMID: 22795341
    7. In this meta-analysis, NINJ2 single-nucleotide polymorphism (SNP) rs12425791 is significantly associated with ischemic stroke in an East Asian (but not Chinese Han) population, of which A alleles increase the risk of ischemic stroke. PMID: 22297388
    8. A new genetic variant rs10849373 located in the first intron of the NINJ2 gene confers risk of ischemic stroke in Chinese Han subjects. PMID: 21722921
    9. 12p13 SNPs rs11833579 and rs12425791 within NINJ2 gene do not seem to be associated with ischemic stroke in Chinese Han population PMID: 21376321
    10. polymorphisms of the vascular susceptibility gene NINJ2 were associated with risk of Alzheimer's disease PMID: 21674003
    11. There is a significant association between rs11833579 site polymorphism of the NINJ2 gene and risk for stroke in Han Chinese. PMID: 20957003

    显示更多

    收起更多

  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ninjurin family
  • 组织特异性：
    Widely expressed. In adult, higher expression in the bone marrow and peripheral blood lymphocytes, medium in the lung, lymph node, thyroid, uterus, thymus, spleen, prostate and skeletal muscle, lower in the liver, placenta, brain, heart and kidney. In emb
  • 数据库链接：

    HGNC: 7825

    OMIM: 607297

    KEGG: hsa:4815

    STRING: 9606.ENSP00000307552

    UniGene: Hs.655804