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NLGN4Y Antibody

  • 货号：
    CSB-PA818786ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NLGN4Y antibody at 6μg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 93, 73, 16, 29 kDa
      Observed band size: 93 kDa
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA818786ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA818786ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NLGN4Y Polyclonal antibody
  • Uniprot No.：
    Q8NFZ3
  • 基因名：
    NLGN4Y
  • 别名：
    ASPGX2 antibody; AUTSX2 antibody; HGNC:14287 antibody; HLNX antibody; HNLX antibody; KIAA0951 antibody; KIAA1260 antibody; MGC22376 antibody; Neuroligin 4 X linked antibody; Neuroligin 4, Y linked antibody; Neuroligin X antibody; Neuroligin Y antibody; Neuroligin-4 antibody; NLGN antibody; NLGN4 antibody; NLGN4X antibody; NLGN4Y antibody; NLGNY_HUMAN antibody; Y-linked antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Neuroligin-4, Y-linked protein (682-816AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Putative neuronal cell surface protein involved in cell-cell-interactions.
  • 基因功能参考文献：
    1. Results suggest an association between a maternal immune response to neuroligin 4 Y-linked (NLGN4Y) and subsequent sexual orientation in male offspring. PMID: 29229842
    2. Results suggest that NLGN4Y is an important negative regulator in prostate cancer progression. PMID: 27626693
    3. Expression of NLGN4Y, a gene that may be involved in synaptic function, is increased in boys with XYY PMID: 25558953
    4. investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777
    5. Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
    6. The coding sequences and splice junctions of the NLGN4Y gene were analyzed in 335 male samples (290 with autism and 45 with mental retardation) to analyze sequence variants in NLGN4Y that are associated with autism or mental retardation. PMID: 18628683

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.
  • 蛋白家族：
    Type-B carboxylesterase/lipase family
  • 组织特异性：
    Expressed in fetal and adult brain, prostate and testis.
  • 数据库链接：

    HGNC: 15529

    OMIM: 400028

    KEGG: hsa:22829

    STRING: 9606.ENSP00000342535

    UniGene: Hs.439199