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NME5 Antibody

  • 货号：
    CSB-PA876464
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA876464(NME5 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA876464(NME5 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    P56597
  • 基因名：
    NME5
  • 别名：
    Inhibitor of p53 induced apoptosis beta antibody; Inhibitor of p53-induced apoptosis-beta antibody; IPIA beta antibody; IPIA-beta antibody; NDK-H 5 antibody; NDK5_HUMAN antibody; NDP kinase homolog 5 antibody; NM23 H5 antibody; nm23-H5 antibody; Nm23-M5 antibody; NM23H5 antibody; NME/NM23 family member 5 antibody; NME5 antibody; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) antibody; Nonmetastatic cells 5, protein expressed in antibody; Nonmetastatic protein 23, homolog 5 antibody; Nucleoside diphosphate kinase homolog 5 antibody; Radial spoke 23 homolog antibody; RSPH23 antibody; Testis specific nm23 homolog antibody; Testis-specific nm23 homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human NME5
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
  • 基因功能参考文献：
    1. study characterized for the first time the human NME5 promoter which is controlled by Sp1 transcription factor in pancreatic cancer PMID: 22564704
    2. found that Nm23-H5 and NDP kinases A and B are differently distributed in spermatids and mature spermatozoa and could therefore be involved at various levels of sperm differentiation and function PMID: 14499630
  • 亚细胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    NDK family
  • 组织特异性：
    Specifically expressed in testis germinal cells.
  • 数据库链接：

    HGNC: 7853

    OMIM: 603575

    KEGG: hsa:8382

    STRING: 9606.ENSP00000265191

    UniGene: Hs.730856