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NMT2 Antibody

  • 货号：
    CSB-PA213831
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA213831(NMT2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    O60551
  • 基因名：
  • 别名：
    EC 2.3.1.97 antibody; Glycylpeptide N tetradecanoyltransferase 2 antibody; Glycylpeptide N-tetradecanoyltransferase 2 antibody; Myristoyl CoA:protein N myristoyltransferase 2 antibody; Myristoyl-CoA:protein N-myristoyltransferase 2 antibody; N-myristoyltransferase 2 antibody; NMT 2 antibody; NMT2 antibody; NMT2_HUMAN antibody; Peptide N myristoyltransferase 2 antibody; Peptide N-myristoyltransferase 2 antibody; Type II N myristoyltransferase antibody; Type II N-myristoyltransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human NMT2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
  • 基因功能参考文献：
    1. ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID: 26621918
    2. induction of NMT2 may play a central role in dioxin carcinogenicity. PMID: 11731439
    3. NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID: 16123142
    4. Involved in progression and regulation of telomerase PMID: 16364039
    5. Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID: 16530191
    6. Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID: 17568424
    7. Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID: 18089753

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  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    NMT family
  • 数据库链接：

    HGNC: 7858

    OMIM: 603801

    KEGG: hsa:9397

    STRING: 9606.ENSP00000367407

    UniGene: Hs.60339