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NPAP1 Antibody

  • 货号：
    CSB-PA220876
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA220876(NPAP1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9NZP6
  • 基因名：
    NPAP1
  • 别名：
    NPAP1 antibody; C15orf2Nuclear pore-associated protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human NPAP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in spermatogenesis.
  • 基因功能参考文献：
    1. NPAP1 is specific to primate species and absent from the 15q11q13-orthologous regions in all nonprimate mammals. PMID: 24482533
    2. C15orf2 is part of the nuclear pore complex or its associated molecular networks. PMID: 22694955
    3. C15orf2 gene is imprinted, with monoallelic expression from the paternal allele in fetal brain. PMID: 17337158
    4. These results indicate that C15orf2 might have an important role in human biology and that a deficiency of C15orf2 might contribute to Prader-Willi syndrome. PMID: 20020165
    5. The results from this study show an involvement of microdeletions at 15q11.2 that predispose patients to idiopathic generalized epilepsies. PMID: 19843651

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  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus inner membrane. Note=Colocalizes with the NPC and nuclear lamins at the nuclear periphery.
  • 组织特异性：
    Testis-specific in adults. In fetal brain expressed only from the paternal allele.
  • 数据库链接：

    HGNC: 1190

    OMIM: 610922

    KEGG: hsa:23742

    STRING: 9606.ENSP00000333735

    UniGene: Hs.649663