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NTM Antibody

  • 货号：
    CSB-PA880111ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA880111ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA880111ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NTM Polyclonal antibody
  • Uniprot No.：
    Q9P121
  • 基因名：
    NTM
  • 别名：
    hNT antibody; IgLON family member 2 antibody; IGLON2 antibody; Neurotrimin antibody; NT antibody; NTM antibody; NTRI_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Neurotrimin protein (30-316AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Neural cell adhesion molecule.
  • 基因功能参考文献：
    1. NTM is not a susceptibility gene for autism spectrum disorders. PMID: 26334118
    2. Both the AFF3 and NTM triglyceride associations were replicated among Multi-ethnic Study of Atherosclerosis study participants (P = 1.00 x 10(-7) and 8.00 x 10(-5), respectively). PMID: 25819087
    3. The generation and cardiac phenotype of single and double heterozygous gene-targeted OPCML and Neurotrimin knockout mice. PMID: 24616287
    4. A translocation breaks intron 1 of a splicing isoform of Neurotrimin at 11q25 in a family with intracranial and thoracic aortic aneurysm. PMID: 23054244
    5. A quantitative analysis of central corneal thickness and a subsequent analysis of primary open-angle glaucoma (POAG), SNPs in two cell adhesion molecules, NTM and CNTNAP4, were identified and may increase POAG susceptibility in a subset of cases. PMID: 22661486
    6. The finding of this study provided evidence that NTM at 11q25 chromosome regions affecting IQ. PMID: 21036197
    7. Human neurotrimin is expressed on the surface of CHO cells and could strengthen their aggregation. PMID: 15379248
    8. NTM shows close linkage to OPCML on chromosome 11q25. PMID: 12819783

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Immunoglobulin superfamily, IgLON family
  • 数据库链接：

    HGNC: 17941

    OMIM: 607938

    KEGG: hsa:50863

    STRING: 9606.ENSP00000396722

    UniGene: Hs.504352