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NUFIP1 Antibody

  • 中文名称：
    NUFIP1兔多克隆抗体
  • 货号：
    CSB-PA016182GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UHK0
  • 基因名：
    NUFIP1
  • 别名：
    NUFIP1 antibody; Nuclear fragile X mental retardation-interacting protein 1 antibody; Nuclear FMRP-interacting protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human NUFIP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds RNA.
  • 基因功能参考文献：
    1. NUFIP1 is a receptor for the selective autophagy of ribosomes. PMID: 29700228
    2. Results solve the structure of a complex resulting from interaction between protein fragments of human NUFIP1 and its cofactor ZNHIT3, and emphasize their imbrication. Also, it seems that the complexes involving NUFIP1, ZNHIT3, and SNU13 share strong structural similarities between human and yeast, suggesting that the initial steps of the box C/D snoRNP assembly process are conserved among species. PMID: 27594683
    3. NUFIP is associated with preinitiation complexes, open transcription complexes, and elongation complexes and facilitates ATP-dependent dissociation of hyperphosphorylated pol II from open transcription complexes in vitro PMID: 15107825
  • 亚细胞定位：
    Nucleus. Note=Distributed in the nucleus in a dot-like pattern.
  • 组织特异性：
    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
  • 数据库链接：

    HGNC: 8057

    OMIM: 604354

    KEGG: hsa:26747

    STRING: 9606.ENSP00000368459

    UniGene: Hs.525006