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NUP210 Antibody

  • 货号：
    CSB-PA016195GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8TEM1
  • 基因名：
  • 别名：
    FLJ22389 antibody; GP 210 antibody; KIAA0906 antibody; Nuclear envelope pore membrane protein POM 210 antibody; Nuclear pore membrane glycoprotein 210 antibody; Nuclear pore protein gp210 antibody; Nucleoporin 210 antibody; Nucleoporin 210kDa antibody; Nucleoporin Nup210 antibody; Nucleoporin210 antibody; NUP 210 antibody; Nup210 antibody; PO210_HUMAN antibody; POM 210 antibody; POM210 antibody; Pore membrane protein of 210 kDa antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human NUP210
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
  • 基因功能参考文献：
    1. solution structure of the C-terminal domain PMID: 12653556
    2. gp210 plays critical roles at the nuclear membrane PMID: 14517331
    3. WT1 is probably not regulating GP210 expression, in spite of binding sites for WT1 PMID: 15613247
    4. Quantitation of serusm anti-gp210-C-terminal peptide antibodies is useful for monitoring the effect of ursodeoxycholic acid and for the early identification of patients at high risk for end-stage hepatic failure. PMID: 15710222
    5. The increased expression of gp210 in small bile ducts is possibly involved in autoimmune response to gp210 leading to the progression to end-stage hepatic failure in primary biliary cirrhosis . PMID: 16337775
    6. Double knockdowns of gp210 in HeLa cells suggest that nuclear pore complexes can assemble or at least persist in a gp210-free form. PMID: 16702234

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  • 亚细胞定位：
    Nucleus, nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    NUP210 family
  • 组织特异性：
    Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 30052

    OMIM: 607703

    KEGG: hsa:23225

    STRING: 9606.ENSP00000254508

    UniGene: Hs.475525