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NXN Antibody

  • 货号：
    CSB-PA016224HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, A549 whole cell lysate
      All lanes: NXN antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 49, 21, 37 kDa
      Observed band size: 49 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NXN Polyclonal antibody
  • Uniprot No.：
    Q6DKJ4
  • 基因名：
    NXN
  • 别名：
    FLJ12614 antibody; NRX antibody; nucleoredoxin 1 antibody; Nucleoredoxin antibody; Nxn antibody; NXN_HUMAN antibody; OTTHUMP00000115356 antibody; TRG 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Nucleoredoxin protein (155-435AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NXN Antibody (CSB-PA016224HA01HU)，的标记方式是Non-conjugated。对于NXN Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA016224HB01HU NXN Antibody, HRP conjugated ELISA
    FITC CSB-PA016224HC01HU NXN Antibody, FITC conjugated
    Biotin CSB-PA016224HD01HU NXN Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
  • 基因功能参考文献：
    1. identified nucleoredoxin as an interaction partner of Sec63; characterized this interaction; Sec63 is linked to the Wnt signaling pathways and this interaction may be the reason why mutations in SEC63 can lead to polycystic liver disease PMID: 21251912
    2. Nucleoredoxin is a novel thioredoxin family member involved in cell growth and differentiation [review] PMID: 17567240
  • 亚细胞定位：
    Cytoplasm, cytosol. Nucleus.
  • 蛋白家族：
    Nucleoredoxin family
  • 数据库链接：

    HGNC: 18008

    OMIM: 612895

    KEGG: hsa:64359

    STRING: 9606.ENSP00000337443

    UniGene: Hs.527989