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OCIAD1 Antibody

  • 货号：
    CSB-PA221218
  • 规格：
    ￥1100
  • 图片：
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, Jurkat cells, human testis tissue, 231 cells, Primary antibody: CSB-PA221218(OCIAD1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q9NX40
  • 基因名：
    OCIAD1
  • 别名：
    Asrij antibody; FLJ20455 antibody; MGC111072 antibody; OCAD1_HUMAN antibody; OCIA antibody; OCIA domain containing 1 antibody; OCIA domain-containing protein 1 antibody; OCIAD1 antibody; Ovarian carcinoma immunoreactive antigen antibody; TPA018 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human OCIAD1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
  • 基因功能参考文献：
    1. Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
    2. OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
    3. This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
    4. Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
  • 亚细胞定位：
    Endosome.
  • 蛋白家族：
    OCIAD1 family
  • 组织特异性：
    Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
  • 数据库链接：

    HGNC: 16074

    KEGG: hsa:54940

    STRING: 9606.ENSP00000264312

    UniGene: Hs.518750