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OGG1 Antibody

  • 中文名称：
    OGG1兔多克隆抗体
  • 货号：
    CSB-PA727222XA01DOA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: OGG1 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 27.4 kDa
      Observed band size: 29 kDa
  • 其他：

产品详情

  • Uniprot No.：
    Q9FNY7
  • 基因名：
  • 别名：
    N-glycosylase/DNA lyase OGG1 [Includes: 8-oxoguanine DNA glycosylase 1 (AtOGG1) (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] OGG1 At1g21710 F8K7.14
  • 反应种属：
    Escherichia coli (strain K12)
  • 免疫原：
    Recombinant Arabidopsis thaliana OGG1 protein
  • 免疫原种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in repair of DNA damaged by oxidation by incising DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (Fapy) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
  • 基因功能参考文献：
    1. Arabidopsis cells use both FPG and OGG1 to repair 8-oxoG in a pathway that requires ZDP and ARP in downstream steps. PMID: 24934622
    2. Overexpression of OGG1 enhances seed longevity and abiotic stress tolerance. PMID: 22473985
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Type-1 OGG1 family
  • 组织特异性：
    Expressed in stems, roots, rosette and cauline leaves, flowers and seeds.
  • 数据库链接：

    KEGG: ath:AT1G21710

    STRING: 3702.AT1G21710.1

    UniGene: At.10191