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OSGEP Antibody

  • 货号：
    CSB-PA878842ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: OSGEP antibody at 2.04µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: PC-3 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36 kDa
      Observed band size: 36 kDa
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA878842ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) OSGEP Polyclonal antibody
  • Uniprot No.：
    Q9NPF4
  • 基因名：
    OSGEP
  • 别名：
    FLJ20411 antibody; GCPL-1 antibody; GCPL1 antibody; hOSGEP antibody; KAE1 antibody; O sialoglycoprotein endopeptidase antibody; OSGEP antibody; OSGEP_HUMAN antibody; OSGEP1 antibody; Pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1 antibody; Probable O sialoglycoprotein endopeptidase antibody; Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep antibody; PRSMG1 antibody; Prsmg1/Gcpl1 antibody; t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Probable tRNA N6-adenosine threonylcarbamoyltransferase protein (1-335AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
  • 基因功能参考文献：
    1. Mutation in KAE1 interfering with global protein production was identified in two patients with developmental delay, renal defect and hypomagnesemia. PMID: 28272532
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    KAE1 / TsaD family
  • 组织特异性：
    Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas.
  • 数据库链接：

    HGNC: 18028

    OMIM: 610107

    KEGG: hsa:55644

    STRING: 9606.ENSP00000206542

    UniGene: Hs.525196