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  4. PABPC4 Antibody

PABPC4 Antibody

  • 货号：
    CSB-PA017357GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13310
  • 基因名：
  • 别名：
    Activated platelet protein 1 antibody; Activated-platelet protein 1 antibody; APP 1 antibody; APP-1 antibody; APP1 antibody; FLJ43938 antibody; Inducible poly(A) binding protein antibody; Inducible poly(A)-binding protein antibody; iPABP antibody; IPABP4 antibody; PABP 4 antibody; PABP-4 antibody; PABP4 antibody; PABP4_HUMAN antibody; PABPC 4 antibody; PABPC4 antibody; Poly A binding protein cytoplasmic 4 antibody; Poly(A) binding protein 4 antibody; Poly(A) binding protein cytoplasmic 4 (inducible form) antibody; Poly(A) binding protein cytoplasmic 4 antibody; Poly(A)-binding protein 4 antibody; Polyadenylate binding protein 4 antibody; Polyadenylate-binding protein 4 antibody; Polyadenylate-binding protein; cytoplasmic; 4 antibody; Polyadenylate-binding protein; inducible antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PABPC4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
  • 基因功能参考文献：
    1. The PABPC4 rs4660293 SNP is associated with serum lipid levels. PMID: 26005159
    2. PABPC4 is highly expressed in human colorectal cancer. PMID: 22884093
    3. Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export PMID: 21940797
    4. RNA binding masks nuclear import signals within the cytoplasmic poly(A) binding protein RNA recognition motifs, thereby ensuring ef fi cient cytoplasmic retention of this protein in normal cells PMID: 21646427
  • 亚细胞定位：
    Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • 蛋白家族：
    Polyadenylate-binding protein type-1 family
  • 组织特异性：
    Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.
  • 数据库链接：

    HGNC: 8557

    OMIM: 603407

    KEGG: hsa:8761

    STRING: 9606.ENSP00000361949

    UniGene: Hs.169900