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PARP6 Antibody

  • 货号：
    CSB-PA017470GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q2NL67
  • 基因名：
    PARP6
  • 别名：
    1700119G14Rik antibody; 2310028P13Rik antibody; 3110038K10Rik antibody; ADP-ribosyltransferase diphtheria toxin-like 17 antibody; ARTD17 antibody; C030013N01Rik antibody; MGC131971 antibody; PARP 6 antibody; PARP 6 B1 antibody; PARP 6 C antibody; PARP-6 antibody; PARP6 antibody; PARP6_HUMAN antibody; pART17 antibody; poly (ADP ribose) polymerase family; member 6 antibody; Poly [ADP ribose] polymerase 6 antibody; Poly [ADP-ribose] polymerase 6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PARP6
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
  • 基因功能参考文献：
    1. Results showed that both PARP6 and survivin exhibited higher expression in colorectal adenocarcinoma tissues and cell lines. knockdown of either PARP6 or survivin promotes cell apoptosis and inhibits the cell invasion of colorectal adenocarcinoma cells suggesting a significant correlation between theses 2 proteins. PMID: 28260087
    2. PARP6 acts as a tumor suppressor via downregulating Survivin expression in CRC. PARP6 can be a novel diagnostic and therapeutic target together with Survivin for CRC. PMID: 26934315
    3. PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development, PARP6-positive colorectal cancer had a good prognosis. PMID: 23042038
  • 数据库链接：

    HGNC: 26921

    KEGG: hsa:56965

    STRING: 9606.ENSP00000287196

    UniGene: Hs.270244