Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. PCDH20 Antibody

PCDH20 Antibody

  • 货号：
    CSB-PA822719LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA822719LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PCDH20 Polyclonal antibody
  • Uniprot No.：
    Q8N6Y1
  • 基因名：
    PCDH20
  • 别名：
    FLJ22218 antibody; PCD20_HUMAN antibody; PCDH 13 antibody; PCDH 20 antibody; PCDH13 antibody; PCDH20 antibody; Protocadherin 13 antibody; Protocadherin 20 antibody; Protocadherin-13 antibody; Protocadherin-20 antibody; Protocadherin13 antibody; Protocadherin20 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protocadherin-20 protein (61-360AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PCDH20 Antibody (CSB-PA822719LA01HU)，的标记方式是Non-conjugated。对于PCDH20 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA822719LB01HU PCDH20 Antibody, HRP conjugated ELISA
    FITC CSB-PA822719LC01HU PCDH20 Antibody, FITC conjugated
    Biotin CSB-PA822719LD01HU PCDH20 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potential calcium-dependent cell-adhesion protein.
  • 基因功能参考文献：
    1. low expression of PCDH20 was found to be associated with poor OS in HCC patients; hence, this protein represents a promising potential prognostic biomarker PMID: 27935871
    2. Study shows that PCDH20 expression is downregulated in nasopharyngeal carcinoma cells (NPC) and identified it as a functional tumor suppressor and an important antagonist of Wnt/beta-catenin signaling and EMT, with frequent epigenetic inactivation in NPC. PMID: 25736877
    3. In conclusion, these data here strongly suggested that PCDH20 may act as a candidate tumour suppressor in hepatocellular carcinoma. PMID: 24910204
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 数据库链接：

    HGNC: 14257

    OMIM: 614449

    KEGG: hsa:64881

    STRING: 9606.ENSP00000386653

    UniGene: Hs.391781