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PCF11 Antibody

  • 货号：
    CSB-PA017603LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA017603LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA017603LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PCF11 Polyclonal antibody
  • Uniprot No.：
    O94913
  • 基因名：
    PCF11
  • 别名：
    hPCF11 antibody; KIAA0824 antibody; OTTHUMP00000234826 antibody; PCF11 antibody; PCF11 cleavage and polyadenylation factor subunit antibody; PCF11; cleavage and polyadenylation factor II subunit; homolog antibody; PCF11; cleavage and polyadenylation factor subunit; homolog (S. antibody; PCF11_HUMAN antibody; PCF11p homolog antibody; Pre-mRNA cleavage complex 2 protein Pcf11 antibody; Pre-mRNA cleavage complex II protein Pcf11 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Pre-mRNA cleavage complex 2 protein Pcf11 protein (409-604AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PCF11 Antibody (CSB-PA017603LA01HU)，的标记方式是Non-conjugated。对于PCF11 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA017603LB01HU PCF11 Antibody, HRP conjugated ELISA
    FITC CSB-PA017603LC01HU PCF11 Antibody, FITC conjugated
    Biotin CSB-PA017603LD01HU PCF11 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of pre-mRNA cleavage complex II.
  • 基因功能参考文献：
    1. WNK1 and the associated phosphorylation of the PCF11 CID act to promote transcript release from chromatin-associated Pol II, which in turn facilitates mRNA export to the cytoplasm PMID: 29196535
    2. Pcf11 can act as a negative elongation factor to repress RNA Pol II gene expression in eukaryotic cells. PMID: 17606639
    3. Pcf11 is required for the efficient degradation of the 3' product of poly(A) site cleavage. PMID: 18086705
    4. Human PCf11 is a pre-mRNA processing factor. PMID: 11060040
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 30097

    OMIM: 608876

    KEGG: hsa:51585

    STRING: 9606.ENSP00000298281

    UniGene: Hs.128959