Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. PDE6H Antibody

PDE6H Antibody

  • 货号：
    CSB-PA617840LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA617840LA01HU diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PDE6H Polyclonal antibody
  • Uniprot No.：
    Q13956
  • 基因名：
    PDE6H
  • 别名：
    5''-cyclic phosphodiesterase subunit gamma antibody; CNCG_HUMAN antibody; GMP-PDE gamma antibody; Pde6h antibody; Retinal cone rhodopsin-sensitive cGMP 3'' antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma protein (1-83AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PDE6H Antibody (CSB-PA617840LA01HU)，的标记方式是Non-conjugated。对于PDE6H Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA617840LB01HU PDE6H Antibody, HRP conjugated ELISA
    FITC CSB-PA617840LC01HU PDE6H Antibody, FITC conjugated
    Biotin CSB-PA617840LD01HU PDE6H Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
  • 基因功能参考文献：
    1. These findings add PDE6H to the set of genes involved in autosomal-recessive cone disorders and demonstrate the importance of the inhibitory gamma subunit in cone phototransduction PMID: 22901948
    2. Our results indicate that mutations in the PDE6H gene are not common, because only 1 of 240 patients with cone dystrophy showed a single nucleotide substitution in the 5' UTR of PDE6H mRNA PMID: 15629837
  • 相关疾病：
    Cone dystrophy, retinal 3A (RCD3A)
  • 蛋白家族：
    Rod/cone cGMP-PDE gamma subunit family
  • 数据库链接：

    HGNC: 8790

    OMIM: 601190

    KEGG: hsa:5149

    STRING: 9606.ENSP00000266395

    UniGene: Hs.54471