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PEX10 Antibody

  • 货号：
    CSB-PA017794LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat brain tissue, Mouse brain tissue
      All lanes: PEX10 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 38, 40 kDa
      Observed band size: 38 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PEX10 Polyclonal antibody
  • Uniprot No.：
    O60683
  • 基因名：
    PEX10
  • 别名：
    AV128229 antibody; Gm142 antibody; MGC1998 antibody; NALD antibody; OTTHUMP00000001658 antibody; PBD6A antibody; PBD6B antibody; peroxin 10 antibody; Peroxin-10 antibody; Peroxisomal biogenesis factor 10 antibody; Peroxisome assembly protein 10 antibody; Peroxisome biogenesis factor 10 antibody; PEX10 antibody; PEX10_HUMAN antibody; RING finger protein 69 antibody; RNF69 antibody; RP23-298E4.1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat, Mouse
  • 免疫原：
    Recombinant Human Peroxisome biogenesis factor 10 protein (63-157AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PEX10 Antibody (CSB-PA017794LA01HU)，的标记方式是Non-conjugated。对于PEX10 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA017794LB01HU PEX10 Antibody, HRP conjugated ELISA
    FITC CSB-PA017794LC01HU PEX10 Antibody, FITC conjugated
    Biotin CSB-PA017794LD01HU PEX10 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Somewhat implicated in the biogenesis of peroxisomes.
  • 基因功能参考文献：
    1. This study demonstrated that two mutations in PEX10 were found in the three peroxisomal biogenesis disorders patients: c.827G>T (novel) causing the missense change p.Cys276Phe and c.932G>A causing the missense change p.Arg311Gln. PMID: 27230853
    2. abnormal expression of PEX10 gene resulting from copy number variations of 1p36 region may be associated with the epilepsy phenotype PMID: 25636090
    3. child and an adult of normal intelligence with progressive ataxia, axonal motor neuropathy, decreased vibration sense and cerebellar atrophy; 2 mutations in PEX10 found in child, c.992G>A and c.764_765insA, and in the adult, c.2T>C and c.790C>T PMID: 20695019
    4. Genetic heterogeneity in Japanese patients with peroxisome biogenesis disorders and evidence for a founder haplotype for the most common mutation in PEX10 gene. PMID: 14713216
    5. the relative fraction of disease-causing alleles that occur in the coding and splice junction sequences of PEX10 gene. PMID: 19105186

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  • 相关疾病：
    Peroxisome biogenesis disorder complementation group 7 (PBD-CG7); Peroxisome biogenesis disorder 6A (PBD6A); Peroxisome biogenesis disorder 6B (PBD6B)
  • 亚细胞定位：
    Peroxisome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Pex2/pex10/pex12 family
  • 数据库链接：

    HGNC: 8851

    OMIM: 602859

    KEGG: hsa:5192

    UniGene: Hs.732228