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PEX2 Antibody

  • 中文名称：
    PEX2兔多克隆抗体
  • 货号：
    CSB-PA003742
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using Peroxin 2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P28328
  • 基因名：
    PEX2
  • 别名：
    PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72; Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Peroxin 2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Somewhat implicated in the biogenesis of peroxisomes.
  • 基因功能参考文献：
    1. PEX2 is required for peroxisome autophagy during starvation. PMID: 27597759
    2. the carrier frequencies for two PEX2 mutations causative of the severe Zellweger syndrome spectrum phenotype in Ashkenazi Jews PMID: 23590336
    3. Ischemic wound healing is retarded in mice subjected to recombinant PEX2 injections or viral transduction with PEX2-lentivurus. PMID: 21903356
    4. Genetic screening of PEX2 and other PEX genes involved in peroxisomal biogenesis is warranted in children and adults with ARCA PMID: 21392394
    5. The cause of the syndrome in this patient was a point mutation that resulted in the premature termination of peroxisome assembly factor-1. PMID: 1546315

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  • 相关疾病：
    Peroxisome biogenesis disorder complementation group 5 (PBD-CG5); Peroxisome biogenesis disorder 5A (PBD5A); Peroxisome biogenesis disorder 5B (PBD5B)
  • 亚细胞定位：
    Peroxisome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Pex2/pex10/pex12 family
  • 数据库链接：

    HGNC: 9717

    OMIM: 170993

    KEGG: hsa:5828

    STRING: 9606.ENSP00000349543

    UniGene: Hs.437966