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PFDN2 Antibody

  • 货号：
    CSB-PA017813LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PFDN2 antibody at 6µg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 17 kDa
      Observed band size: 17 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA017813LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA017813LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PFDN2 Polyclonal antibody
  • Uniprot No.：
    Q9UHV9
  • 基因名：
    PFDN2
  • 别名：
    OTTHUMP00000029707 antibody; PFD2 antibody; PFD2_HUMAN antibody; PFDN2 antibody; prefoldin 2 antibody; Prefoldin subunit 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Prefoldin subunit 2 protein (1-154AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PFDN2 Antibody (CSB-PA017813LA01HU)，的标记方式是Non-conjugated。对于PFDN2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA017813LB01HU PFDN2 Antibody, HRP conjugated ELISA
    FITC CSB-PA017813LC01HU PFDN2 Antibody, FITC conjugated
    Biotin CSB-PA017813LD01HU PFDN2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
  • 基因功能参考文献：
    1. prefoldin is amplified at 1q23.3-q24.1 in bladder cancer PMID: 23914742
    2. knockdown of PFD2 and PFD5 disrupted prefoldin formation in HTT-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT and in induction of cell death. PMID: 23720755
    3. Is part of an RNA polymerase II-associated complex with possible chaperone activity. PMID: 19450687
  • 亚细胞定位：
    Nucleus. Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Prefoldin subunit beta family
  • 数据库链接：

    HGNC: 8867

    OMIM: 613466

    KEGG: hsa:5202

    STRING: 9606.ENSP00000356989

    UniGene: Hs.492516