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PFDN5 Antibody

  • 货号：
    CSB-PA01415A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA01415A0Rb at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA01415A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA01415A0Rb at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PFDN5 Polyclonal antibody
  • Uniprot No.：
    Q99471
  • 基因名：
    PFDN5
  • 别名：
    1190001O17Rik antibody; 1700010A06Rik antibody; c myc binding protein antibody; c-myc binding protein MM 1 antibody; C-myc-binding protein Mm-1 antibody; D15Ertd697e antibody; EIG 1 antibody; Eig1 antibody; MGC5329 antibody; MGC71907 antibody; MM 1 antibody; MM1 antibody; Myc modulator 1 antibody; PFD5 antibody; PFD5_HUMAN antibody; PFDN5 antibody; Prefoldin 5 antibody; Prefoldin subunit 5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Prefoldin subunit 5 protein (2-154AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PFDN5 Antibody (CSB-PA01415A0Rb)，的标记方式是Non-conjugated。对于PFDN5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA01415B0Rb PFDN5 Antibody, HRP conjugated ELISA
    FITC CSB-PA01415C0Rb PFDN5 Antibody, FITC conjugated
    Biotin CSB-PA01415D0Rb PFDN5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
  • 基因功能参考文献：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that PFDN5 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. interaction with p73 PMID: 11844794
    3. MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc PMID: 16173081
    4. Wnt4 gene, a member of the Wnt-beta-catenin pathway, was identified as a target gene of MM-1. PMID: 18281035
  • 亚细胞定位：
    [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.
  • 蛋白家族：
    Prefoldin subunit alpha family
  • 组织特异性：
    Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
  • 数据库链接：

    HGNC: 8869

    OMIM: 604899

    KEGG: hsa:5204

    STRING: 9606.ENSP00000334188

    UniGene: Hs.655327