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PGA3 Antibody

  • 货号：
    CSB-PA11289A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PGA3 Polyclonal antibody
  • Uniprot No.：
    P0DJD8
  • 基因名：
    PGA3
  • 别名：
    PGA3 antibody; Pepsin A-3 antibody; EC 3.4.23.1 antibody; Pepsinogen-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Pepsin A-3 protein (16-388AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PGA3 Antibody (CSB-PA11289A0Rb)，的标记方式是Non-conjugated。对于PGA3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA11289B0Rb PGA3 Antibody, HRP conjugated ELISA
    FITC CSB-PA11289C0Rb PGA3 Antibody, FITC conjugated
    Biotin CSB-PA11289D0Rb PGA3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
  • 基因功能参考文献：
    1. Low Pepsinogen I is associated with precancerous gastric lesions. PMID: 25292040
    2. High serum Pepsinogen I level is associ9ated with the progression of gastric precancerous lesions. PMID: 24895149
    3. Significantly higher AUC was observed for the PGI/PGII ratio and is associated with atrophy and intestinal metaplasia. PMID: 23886209
    4. A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I in atrophic gastritis patients with gastroesophageal reflux. PMID: 21175799
    5. Higher levels of Pepsinogen I is associated with early gastric cancer PMID: 15688378
    6. Helicobacter pylori eradication improves gastric histology and decreases serum gastrin, pepsinogen I and pepsinogen II levels in patients with duodenal ulcer. PMID: 17559360
    7. pepsinogens may have a role in esophageal squamous dysplasia PMID: 18844222
    8. Barrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan. PMID: 19196398

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase A1 family
  • 数据库链接：

    HGNC: 8885

    OMIM: 169700

    KEGG: hsa:643834

    STRING: 9606.ENSP00000322192

    UniGene: Hs.601055